Prevage MD vs Generic Idebenone

Categories: Anti-aging, Beauty Products, Skin care
Leave A Comment: Comments(13)

prevage mdPrevage MD
When I worked at the Medical Spa, we sold Prevage MD, the 1% Idebenone cream that is made by Allergan, the makers of Botox. This normally retails for about $150 (although we were selling it for $100 for some reason), so I was excited that we had a tester to use since I was extremely curious to see if the cream lived up to the hype. Idebenone is touted as one of the most powerful topical antioxidants for use in skin care. Prevage MD states that its use will reduce the appearance of fine lines and wrinkles, roughness and dryness, and it will even out skin tone, giving your skin a more youthful appearance. Fabulous!

Following the directions, I applied a small amount of the product at night. The next day I woke up with some clogged pores – whiteheads mostly. Sorry if I’m grossing you out! I tried Prevage a few more times after that and broke out every time, so I stopped using it. Three other people I worked with at the Medical Spa also tried Prevage MD, and while their skin didn’t break out, they all developed red rashes within two weeks! I did an internet search and saw that this is extremely common with the product. I’ve had clients come in and say they have had good results with Prevage MD, so it obviously works for some people, but I’ve never heard of so many people having problems with a product!

The Prevage MD directions do state to do a patch test before you use it, and it’s best not to mix it with retinoids or other aggressive skin treatments. When I read the ingredients of the product, Algae Extract is listed. If you look at my Cosmetic Acne list of ingredients to avoid, you will see Algae Extract is extremely pore-clogging. So I wouldn’t recommend Prevage MD for acne-prone skin. Nor would I recommend it for sensitive skin. If you do purchase it, I would get it from a place that accepts returns, since you don’t want to waste your money if you get a rash!

Want To Try Prevage? (not recommended for acne-prone or sensitive skin)

Generic Idebenone
A friend of mine has been working with Idebenone for several years. Even though Prevage MD retails for $150, Idebenone is an inexpensive ingredient. I wanted to see if it was the Prevage MD or the Idebenone in the Prevage MD that made my skin break out, so my friend mixed me up a 1% Idebenone cream. He actually mixed the Idebenone in a moisturizer I use all the time and have no problems with Olay Regenerist Deep Hydration Regenerating Cream. I applied the cream for several nights and didn’t have any reaction to it. So it must be something in the Prevage MD that is problematic to my skin. I’ve also been using the cream off and on for several weeks now and haven’t developed a rash. Whether or not I will see a change in my fine lines and wrinkles is still up in the air, but I will keep you posted!

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13 Responses to “Prevage MD vs Generic Idebenone”

  1. Marina P Says:

    I can’t wait to hear about your results. I have been using HydroPeptide. I love the results I’ve seen with it. Its not touted as an antioxidant creme like Prevage but as an all-in-one anti-aging creme. It has a very high percentage of antioxidants though. It has over 10. Not only that, it has peptides. Six of them. I love peptides. I love this product. My skin has never looked this good. Do you know if there are any studies done comparing peptides to idebenone in regards to collagen production and wrinkle reduction?

  2. Jeni Says:

    Hmm that creme you use sounds good! I haven’t found any studies that compare peptides to idebenone, but I will be on the lookout for them. I know you can’t go wrong with either antioxidants, or peptides, but I have yet to figure out if one is better than the other. If you find out anything either, let me know! Thanks!

  3. Erika Says:

    Last weekend I was in San Francisco and they had their baby formula locked up! People will steal anything these days. Sad.

  4. Terinea Weblog Says:

    Thanks for dropping by.

    A good example for one of my clients

    Keep up the blog

    Jamie at Terinea

  5. Christine Says:

    Thanks for the heads up about patch testing and generic comparison!

  6. Maria Says:

    I started using Prevage MD two weeks ago, after the 2 or 3 aplication once a day I notice mild acne on my forehead .I had read about the high incidence of skin reactions reported by others using this product , so I stoped using it for a couple of days, the pimples clear out with no problem . I am only using very small amouts every other day now, and so far so good. I wonder if its better to use at night or in the morning . Any suggestions?I am eager to see some good results soon.

  7. Jeni - Savvy Skin Says:

    If you are getting mild acne from the Prevage, I’m not sure if it will go away with continued use or not. I’m pretty sure it’s one of the ingredients (algae extract) in the product that causes cosmetic acne in a lot of people. If you continue to use it, though, after a month or two, you should start seeing some results with the Prevage MD. Just make sure to use sunscreen when you go out. It doesn’t matter if you use the product at night, or in the morning.

    As far as the results Prevage is supposed to provide, I think using a Retinol product might give you better results in the long run, along with using a good sunscreen.

  8. Kellye Says:

    That’s too bad you’re getting acne with this AMAZING product! I’ve been using Prevage MD for two years now and love love love it!! I refuse to use anything else to brighten, tighten, smooth and leave my skin glowing.
    Perhaps you should try the regular Prevage, they put MD on it for a reason.

  9. wandrwoman Says:

    I have been using Prevage MD for several months now and am very happy with the results. My biggest problem is the cost! Could you explain where to get the generic Idebenone and how to mix it into the moisturizer? This would be a great solution but I am afraid of not doing it properly! Thanks so much for any information!

  10. Ashley Says:

    In Canada we don’t have Prevage MD, we just have Prevage which boasts a .05% Idebenone. I work in a commercial cosmetics sales environment where we sell the regular Prevage. I use it every second night, and in between I use Neostrata’s 8% glycolic smoothing cream. The glycolic keeps any adverse acne affects at bay, and sloughs away my dead skin cells allowing the Prevage to penetrate only healthy skin cells.

  11. collett Says:

    I have been using Prevage MD for almost three weeks now, and my skin looks smoother. I have a bit of a rash on my forehead, but it could also be due to my period that should start soon. I have however seen a very noticeble change on my neck. I had botox done some time ago, and ever since, my neck looks like an old woman, ( looks like turkey skin), the one “band” is much worse than the other. I have tried several products before, and nothing worked. Prevage MD is the first product that actually really made a difference. It has definetely improved, . I also have a friend that uses Neostrata with Prevage and she is very happy with the results.

  12. Melisa Says:

    I did plenty of research on Prevage MD before trying it, and saw many reviews about rashes and breakouts. I have very sensitive, acne prone, T-Zone oily skin, so this was a great concern. I decided to go for it because I figured if it worked, the long term gain would outlast the negative of dealing with a breakout for a couple weeks.

    So, I am 31 years old and have been using Prevage MD for the last year and a half. It has never caused my skin any irritation or breakouts, and while there were no immediate, significant changes, I stuck with it because it was one of the few moisturizers that didn’t make me breakout, and I liked the feel of it on my skin. Somewhere over the course of the past year and a half, I’ve apparently lost about 5 years in my appearance.

    When I started, I had a lot of acne scars, sagging around my cheek/mouth area, enlarged pores, and was beginning to see the initial signs of aging around my eyes. Now, everyone thinks I’m somewhere between 19-25. I have been carded more in the past year than I have from 25-30. I look at my girlfriends of the same age and they seemed to have aged +5 years as they crossed into the 30-year threshhold, with crows feet, forehead wrinkles, etc. and I strikes me constantly at how much older they look than me. I can’t help but wonder if I didn’t start using Prevage, would my skin have also been like theirs?

    Anyway, here’s my regimen: I wash my face with the Clarisonic (a must-have) and Philosophy’s Purity Made Simple, use Thayer’s aloe vera witch-hazel as a toner, then apply my presciption topical acne treatment (Duac cream, the only thing that works for me). Once that dries, I apply 2 pumps worth of Prevage MD on my face in upward-outward strokes, then the rest of my makeup. Same routine at night, minus makeup. I’ve developed this routine like most women, through trial-and-error. This is the longest I’ve kept the same routine, and if I skimp on a step or use a replacement product, my skin lets me know it!

  13. newcomer Says:

    Hi All,

    I am really new to use Anti Aging creams . I used Clinique before don’t know what to use . There are so many creams can’t make up my mind. I live in canda

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